Neonatology MCQ- Q32

 

PEDIATRIC MCQ  SECTION  Neonatology -   Q32

 

32. A baby boy is born at term by normal vaginal delivery. The mother's blood group is O-ve while the baby's blood group is A+ve The baby was found to be significantly jaundiced at 12 hours of age, and his bilirubin level increased to 25mg/dl, despite phototherapy. He developed irritability, hypertonia, and back arching. What is your probable diagnosis?

A. Neonatal meningitis
B. Bilirubin encephalopathy
C. Inborn error of metabolism
D. Biliary atresia 
E. Neonatal hepatitis

ANSWER= Ans B
Explain:- Kernicterurus or bilirubin encephalopathy caused by increased levels of unconjugated bilirubin. The unbound unconjugated bilirubin can cross the blood-brain barrier because of its lipid solubility. This results in the deposition of bilirubin in brain causing irreversible damage

                             

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